Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity.

The Journal of general virology - 1 Jan 2002

Curran Rebecca, Jameson Claire L, Craggs Joanna K, Grabowska Anna M, Thomson Brian J, Robins Adrian, Irving William L, Ball Jonathan K

Abstract excerpt

Hepatitis C virus (HCV) exists as a complex swarm of genetically related viruses known as a quasispecies. Recent work has shown that quasispecies complexity and evolutionary rates are associated with the outcome of acute infection. Knowledge of how the virus population evolves at different stages of chronic infection is less clear. We have studied rates of evolution of the first hypervariable region (HVR1) of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine Transaminase
Share to Amino Acids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis C

Share to Hepatitis C Antigens

Share to Liver Diseases

Share to Nucleotides

Share to Protein Sorting Signals

Share to Viral Envelope Proteins

Source

Identifiers

PMID: 11752696
DOI: 10.1099/0022-1317-83-1-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity.PMID 11752696Read ↗

Dynamics of hypervariable region 1 variation in hepatitis C virus infection and correlation with clinical and virological features of liver disease.Semantic proximity Read ↗

Acceleration of Hepatitis C Virus Envelope Evolution in Humans Is Consistent with Progressive Humoral Immune Selection during the Transition from Acute to Chronic InfectionSemantic proximity Read ↗

Evolution of Hypervariable Region 1 of Hepatitis C Virus in Primary InfectionSemantic proximity Read ↗

Dynamic coinfection with multiple viral subtypes in acute hepatitis C.Semantic proximity Read ↗

Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo.Semantic proximity Read ↗

Comparative rates of nucleotide sequence variation in the hypervariable region of E1/E2 and the NS5b region of hepatitis C virus in patients with a spectrum of liver disease resulting from a common source of infection.Semantic proximity Read ↗

Hypervariable region 1 sequence stability during hepatitis C virus replication in chimpanzees.Semantic proximity Read ↗

Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients.Semantic proximity Read ↗

Quasispecies of hepatitis C virus and genetic drift of the hypervariable region in chronic type C hepatitis.Semantic proximity Read ↗

Genetic evolution of structural region of hepatitis C virus in primary infection.Semantic proximity Read ↗

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes.Semantic proximity Read ↗

High-resolution phylogenetic analysis of hepatitis C virus adaptation and its relationship to disease progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.