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Article

Mammalian DNA beta-polymerase in base excision repair of alkylation damage.

Progress in nucleic acid research and molecular biology - 1 Jan 2001

Sobol R W, Wilson S H

Abstract excerpt

DNA beta-polymerase (beta-pol) carries out two critical enzymatic reactions in mammalian single-nucleotide base excision repair (BER): DNA synthesis to fill the repair patch and lyase removal of the 5'-deoxyribose phosphate (dRP) group following cleavage of the abasic site by apurinic/apyrimidinic (AP) endonuclease (1). The requirement for beta-pol in single-nucleotide BER is exemplified in mouse fibroblasts with...

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Identifiers

PMID: 11554313
DOI: 10.1016/s0079-6603(01)68090-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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