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Article

Implication of p53 in base excision DNA repair: in vivo evidence.

Oncogene - 24 Jan 2002

Seo Young R, Fishel Melissa L, Amundson Sally, Kelley Mark R, Smith Martin L

Abstract excerpt

The tumor suppressor p53 plays an important role in response to DNA damage, including DNA repair. One DNA repair pathway, nucleotide excision repair (NER), has been well-documented to be regulated by p53. It seemed probable that p53 may affect other DNA repair pathways. We employed matched isogenic pairs of cell lines, wild-type or p53-deficient, to investigate this question using methyl methanesulfonate (MMS), a...

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Identifiers

PMID: 11850801
DOI: 10.1038/sj.onc.1205129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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