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Article

Substrate specificity of the streptococcal cysteine protease.

The Journal of biological chemistry - 30 Nov 2001

Nomizu M, Pietrzynski G, Kato T, Lachance P, Menard R, Ziomek E

Abstract excerpt

The streptococcal pyrogenic exotoxin B (SpeB) is an important factor in mediating Streptococcus pyogenes infections. SpeB is the zymogen of the streptococcal cysteine protease (SCP), of which relatively little is known regarding substrate specificity. To investigate this aspect of SCP function, a series of internally quenched fluorescent substrates was designed based on the cleavage sites identified in the...

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Identifiers

PMID: 11553627
DOI: 10.1074/jbc.M106306200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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