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Article

The M protein is dispensable for maturation of streptococcal cysteine protease SpeB.

Infection and immunity - 1 Feb 2005

Zimmerlein Björn, Park Hae-Sun, Li Shaoying, Podbielski Andreas, Cleary P Patrick

Abstract excerpt

The streptococcal pyrogenic exotoxin B (SpeB) is an important virulence factor of group A streptococci (GAS) with cysteine protease activity. Maturation of SpeB to a proteolytically active form was suggested to be dependent on cell-wall-anchored M1 protein, the major surface protein of GAS (M. Collin and A. Olsen, Mol. Microbiol. 36:1306-1318, 2000). Collin and Olsen showed that mutant GAS strains expressing...

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Identifiers

PMID: 15664926
DOI: 10.1128/IAI.73.2.859-864.2005
PMCID: PMC546975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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