Article
Identification of a novel cerebral malaria susceptibility locus (Berr5) on mouse chromosome 19.
Genes and immunity - 1 Jun 2010
Berghout J, Min-Oo G, Tam M, Gauthier S, Stevenson M M, Gros P
Abstract excerpt
Cerebral malaria (CM) is an acute, generally lethal condition characterized by high fever, seizures and coma. The genetic component to CM can be investigated in mouse models that vary in degree of susceptibility to infection with Plasmodium berghei ANKA. Using survival time to measure susceptibility in an informative F2 cross (n=257), we identified linkage to chromosome 19 (Berr5 (Berghei resistance locus 5),...
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