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Article

Anti-tumor necrosis factor-alpha antibody limits heart failure in a transgenic model.

Circulation - 4 Sept 2001

Kadokami T, Frye C, Lemster B, Wagner C L, Feldman A M, McTiernan C F

Abstract excerpt

BACKGROUND: - Tumor necrosis factor (TNF)-alpha has been implicated in the pathophysiology of congestive heart failure. A strain of transgenic mice (TNF1.6) with cardiac-specific overexpression of TNF-alpha develop congestive heart failure. METHODS AND RESULTS: To determine the effect of anti-TNF...

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Source

Identifiers

PMID: 11535561
DOI: 10.1161/hc3501.096063

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11535561-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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