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Article

Roles of alpha1A- and alpha1B-adrenoceptors in heart: insights from studies of genetically modified mice.

Clinical and experimental pharmacology & physiology - 1 Sept 2007

Woodcock Elizabeth A

Abstract excerpt

1. Several mouse strains have been prepared in which different subtypes of the alpha1-adrenoceptor (AR) are overexpressed or deleted. The phenotypes of the animals generated vary depending on whether the receptors are expressed specifically in heart or generally throughout the animal, but some overall conclusions can be drawn. 2. Heightened activity of alpha1B-AR by overexpressing the receptors leads to depressed...

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Source

Identifiers

PMID: 17645635
DOI: 10.1111/j.1440-1681.2007.04707.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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