Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profiling of alpha(1b)-adrenergic receptor-induced cardiac hypertrophy by oligonucleotide arrays.

Cardiovascular research - 1 Feb 2003

Yun June, Zuscik Michael J, Gonzalez-Cabrera Pedro, McCune Dan F, Ross Sean A, Gaivin Robert, Piascik Michael T, Perez Dianne M

Abstract excerpt

OBJECTIVE: Cardiac hypertrophy is closely associated with the development of cardiomyopathies that lead to heart failure. The alpha(1B) adrenergic receptor (alpha(1)-AR) is an important regulator of the hypertrophic process. Cardiac hypertrophy induced by systemic overexpression of the alpha(1b)-AR in a mouse model does not progress to heart failure. We wanted to explore potential gene expression differences that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Cardiomegaly

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytokine Receptor gp130

Share to Genes, src

Share to Membrane Glycoproteins

Share to Mice, Inbred CBA

Share to Protein-Tyrosine Kinases

Share to Receptors, Adrenergic, alpha-1

Source

Identifiers

PMID: 12566117
DOI: 10.1016/s0008-6363(02)00696-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profiling of alpha(1b)-adrenergic receptor-induced cardiac hypertrophy by oligonucleotide arrays.PMID 12566117Read ↗

Microarray analysis of gene expression after transverse aortic constriction in miceSemantic proximity Read ↗

Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene.Semantic proximity Read ↗

Age-dependent cardiomyopathy and heart failure phenotype in mice overexpressing beta(2)-adrenergic receptors in the heart.Semantic proximity Read ↗

Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophySemantic proximity Read ↗

Aging-associated changes in cardiac gene expressionSemantic proximity Read ↗

Genetic and phenotypic targeting of beta-adrenergic signaling in heart failure.Semantic proximity Read ↗

Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failureSemantic proximity Read ↗

Alterations in apoptotic signaling in human idiopathic cardiomyopathic hearts in failureSemantic proximity Read ↗

Roles of alpha1A- and alpha1B-adrenoceptors in heart: insights from studies of genetically modified mice.Semantic proximity Read ↗

Hypotension, autonomic failure, and cardiac hypertrophy in transgenic mice overexpressing the alpha 1B-adrenergic receptor.Semantic proximity Read ↗

Divergent transcriptional responses to independent genetic causes of cardiac hypertrophySemantic proximity Read ↗

Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.