Article
Concurrent naive and memory CD8(+) T cell responses to an influenza A virus.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2001
Turner S J, Cross R, Xie W, Doherty P C
Abstract excerpt
Memory Thy-1(+)CD8(+) T cells specific for the influenza A virus nucleoprotein (NP(366-374)) peptide were sorted after staining with the D(b)NP(366) tetramer, labeled with CFSE, and transferred into normal Thy-1.2(+) recipients. The donor D(b)NP(366)(+) T cells recovered 2 days later from the spleens of the Thy-1.2(+) hosts showed the CD62L(low)CD44(high)CD69(low) phenotype, characteristic of the population...
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