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Article

Consequences of suboptimal priming are apparent for low-avidity T-cell responses.

Immunology and cell biology - 1 Feb 2012

Venturi Vanessa, Davenport Miles P, Swan Natasha G, Doherty Peter C, Kedzierska Katherine

Abstract excerpt

The emergence of the novel reassortant A(H1N1)-2009 influenza virus highlighted the threat to the global population posed by an influenza pandemic. Pre-existing CD8(+) T-cell immunity targeting conserved epitopes provides immune protection against newly emerging strains of influenza virus, when minimal antibody immunity exists. However, the occurrence of mutations within T-cell antigenic peptides that enable the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

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Source

Identifiers

PMID: 21556018
DOI: 10.1038/icb.2011.36

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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