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Article

PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A.

Scientific reports - 7 Oct 2016

Uddbäck Ida E M, Steffensen Maria A, Pedersen Sara R, Nazerai Loulieta, Thomsen Allan R, Christensen Jan P

Abstract excerpt

Recently, we showed that combined intranasal and subcutaneous immunization with a non-replicating adenoviral vector expressing NP of influenza A, strain PR8, induced long-standing protection against a range of influenza A viruses. However, H-2b mice challenged with an influenza A strain mutated in the dominant NP366 epitope were not efficiently protected. To address this problem, we envision the use of a cocktail...

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Share to Antigens, Differentiation, B-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27713532
DOI: 10.1038/srep35033
PMCID: PMC5054373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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