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Article

Protection and compensation in the influenza virus-specific CD8+ T cell response.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2003

Webby Richard J, Andreansky Samita, Stambas John, Rehg Jerold E, Webster Robert G, Doherty Peter C, Turner Stephen J

Abstract excerpt

Influenza virus-specific CD8+ T cells generally recognize peptides derived from conserved, internal proteins that are not subject to antibody-mediated selection pressure. Prior exposure to any one influenza A virus (H1N1) can prime for a secondary CD8+ T cell response to a serologically different influenza A virus (H3N2). The protection afforded by this recall of established CD8+ T cell memory, although limited,...

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Source

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Identifiers

PMID: 12775762
DOI: 10.1073/pnas.1232449100
PMCID: PMC165859

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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