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Article

Resistance to selective serotonin reuptake inhibitors : role of serotonergic mechanisms

2009-01-01

Abstract excerpt

SSRIs are the mainstay in the treatment of depression. However, approximately 30% of depressed patients do not respond to antidepressants and the causes of resistance to these drugs are largely unknown. Thus, it is necessary to develop experimental models to investigate the neurobiological changes underlying the response to SSRIs. The approach used in this project was the inter-strain comparison of mice, such as D...

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Literature Corpus work
915b1271-ba29-5c65-a0e8-a38049e26826
DOI
10.21954/ou.ro.00010052
Open publication

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