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Article

Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.

American journal of medical genetics - 8 Aug 2001

McIlroy S P, Dynan K B, Vahidassr D J, Lawson J T, Patterson C C, Passmore P

Abstract excerpt

Genetic variation in one of the major APOE receptors in the brain has been associated with increased risk for Alzheimer disease (AD). A C/T polymorphism in exon 3 and a tetranucleotide repeat polymorphism in the 5' region of the low-density lipoprotein receptor-related protein gene have been reported to increase risk in some studies but these reports have not been universally replicated. In addition, genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11496365
DOI: 10.1002/ajmg.1474

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.PMID 11496365Read ↗

Lack of interaction between LRP1 and A2M polymorphisms for the risk of Alzheimer disease.Semantic proximity Read ↗

Association of polymorphisms in the LRP1 and A2M genes with Alzheimer's disease in the northern Chinese Han population.Semantic proximity Read ↗

The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis.Semantic proximity Read ↗

Risk of Alzheimer's disease is associated with a very low-density lipoprotein receptor genotype in Northern Ireland.Semantic proximity Read ↗

Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E promoter and alpha2-macroglobulin polymorphisms are not genetically associated with Chinese late onset Alzheimer's disease.Semantic proximity Read ↗

Association study of the A2M and LRP1 Genes with Alzheimer disease in the Han Chinese.Semantic proximity Read ↗

No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample.Semantic proximity Read ↗

No association between low density lipoprotein receptor genetic variants and Alzheimer's disease risk.Semantic proximity Read ↗

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.Semantic proximity Read ↗

Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population.Semantic proximity Read ↗

Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease.Semantic proximity Read ↗

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