Article
Type I vs type II spiral ganglion neurons exhibit differential survival and neuritogenesis during cochlear development.
Neural development - 11 Oct 2011
Barclay Meagan, Ryan Allen F, Housley Gary D
Abstract excerpt
BACKGROUND: The mechanisms that consolidate neural circuitry are a major focus of neuroscience. In the mammalian cochlea, the refinement of spiral ganglion neuron (SGN) innervation to the inner hair cells (by type I SGNs) and the outer hair cells (by type II SGNs) is accompanied by a 25% loss of SGNs. RESULTS: We investigated the segregation of neuronal loss in the mouse cochlea using β-tubulin and peripherin...
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