Article
Neurotrophin-3 is required for appropriate establishment of thalamocortical connections.
Neuron - 14 Nov 2002
Ma Long, Harada Takayuki, Harada Chikako, Romero Mario, Hebert Jean M, McConnell Susan K, Parada Luis F
Abstract excerpt
In the vertebrate brain, the thalamus serves as a relay and integration station for diverse neuronal information en route from the periphery to the cortex. Formation of the thalamocortical tract occurs during pre- and postnatal development, with distinct thalamic nuclei projecting to specific cortical regions. The molecular forces that underlie the invasion by axons into specific cortical layers followed by...
Topics
- Animals
- Animals, Newborn
- Cell Communication
- Cell Differentiation
- Cerebral Cortex
- Chemotaxis
- DNA-Binding Proteins
- Forkhead Transcription Factors
- Gene Expression Regulation, Developmental
- Growth Cones