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Article

Neurotrophin-3 is a survival factor in vivo for early mouse trigeminal neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 1996

Wilkinson G A, Fariñas I, Backus C, Yoshida C K, Reichardt L F

Abstract excerpt

Mice lacking neurotrophin-3 (NT-3) have been shown previously to be born with severe sensory deficits. This study characterizes the developmental course of this deficit in the trigeminal sensory ganglion, which in NT-3 homozygous mutants contains only 35% of the normal number of neurons at birth. At embryonic day 10.5 (E10.5), normal numbers of neurons, as assessed by expression of neurofilament protein and of...

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Identifiers

PMID: 8922422
PMCID: PMC2688699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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