Article
Neurotrophin-3 is a survival factor in vivo for early mouse trigeminal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 1996
Wilkinson G A, Fariñas I, Backus C, Yoshida C K, Reichardt L F
Abstract excerpt
Mice lacking neurotrophin-3 (NT-3) have been shown previously to be born with severe sensory deficits. This study characterizes the developmental course of this deficit in the trigeminal sensory ganglion, which in NT-3 homozygous mutants contains only 35% of the normal number of neurons at birth....
Topics
- Animals
- Cell Survival
- Embryo, Mammalian
- Embryonic and Fetal Development
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mutation
- Nerve Growth Factors
- Neurons
- Neurotrophin 3
- Reference Values
- Tissue Distribution
- Trigeminal Ganglion