Article
The anti-initial transcribed sequence, a portable sequence that impedes promoter escape, requires sigma70 for function.
The Journal of biological chemistry - 12 Oct 2001
Chan C L, Gross C A
Abstract excerpt
The anti-sequence, a portable element extending from +1 to +15 of the transcript, is sufficient to prevent promoter escape from a variety of strong final sigma70 promoters. We show here that this sequence does not function with even the strongest final sigma32 promoter. Moreover, a particular class of substitutions in final sigma70 that disrupt interaction between Region 2.2 of final sigma70 and a coiled-coiled...
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