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Article

IKKgamma /NEMO facilitates the recruitment of the IkappaB proteins into the IkappaB kinase complex.

The Journal of biological chemistry - 28 Sept 2001

Yamamoto Y, Kim D W, Kwak Y T, Prajapati S, Verma U, Gaynor R B

Abstract excerpt

IKKgamma/NEMO is an essential regulatory component of the IkappaB kinase complex that is required for NF-kappaB activation in response to various stimuli including tumor necrosis factor-alpha and interleukin-1beta. To investigate the mechanism by which IKKgamma/NEMO regulates the IKK complex, we examined the ability of IKKgamma/NEMO to recruit the IkappaB proteins into this complex. IKKgamma/NEMO binding to...

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Identifiers

PMID: 11470788
DOI: 10.1074/jbc.M104090200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IKKgamma /NEMO facilitates the recruitment of the IkappaB proteins into the IkappaB kinase complex.PMID 11470788Read ↗

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