Article
Identifying post-translational modifications of NEMO by tandem mass spectrometry after high affinity purification.
Protein expression and purification - 1 Nov 2013
Jackson Shawn S, Coughlin Emma E, Coon Joshua J, Miyamoto Shigeki
Abstract excerpt
An integral component of NF-κB signalling is NEMO, NF-κB essential modulator, a regulatory protein of the IκB kinase (IKK) complex. Post-translational modifications of NEMO, including phosphorylation, SUMOylation, and ubiquitination are critical events during stimuli induced NF-κB activation. Her...
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