Article
IKKgamma inhibits activation of NF-kappaB by NIK.
Molecules and cells - 31 Oct 2004
Kwon Woo Jong, Kim Sun Hee, Park Yeo Ok, Cho Mong, Kang Chi Dug, Lee Gwang, An Woo Gun, Joo Woo Hong, Kim Dong Wan
Abstract excerpt
IKKgamma is a component of the IKK complex, which regulates NF-kappaB activity. To investigate the role of IKKgamma, we expressed wild type IKKgamma containing 412 amino acids, and deletion mutants containing residues 1-312 and 101-412, using murine IKKgamma cDNA. In a co-transfection assay with...
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