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Article

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation.

Molecular and cellular biology - 1 Sept 2002

Makris Constantin, Roberts Jaclyn L, Karin Michael

Abstract excerpt

IkappaB kinase gamma (IKKgamma) (also known as NEMO, Fip-3, and IKKAP-1) is the essential regulatory component of the IKK complex; it is required for NF-kappaB activation by various stimuli, including tumor necrosis factor alpha (TNF-alpha), interleukin 1 (IL-1), phorbol esters, lipopolysaccharides, and double-stranded RNA. IKKgamma is encoded by an X-linked gene, deficiencies in which may result in two human...

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Identifiers

PMID: 12192055
DOI: 10.1128/MCB.22.18.6573-6581.2002
PMCID: PMC135629

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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