Article
Expression of functional receptor-coupled TRPC3 channels in DT40 triple receptor InsP3 knockout cells.
The Journal of biological chemistry - 7 Sept 2001
Venkatachalam K, Ma H T, Ford D L, Gill D L
Abstract excerpt
The TRPC3 channel, an intensively studied member of the widely expressed transient receptor potential (TRP) family, is a Ca(2+)-conducting channel activated in response to phospholipase C-coupled receptors. Despite scrutiny, the receptor-induced mechanism to activate TRPC3 channels remains unclear. Evidence indicates TRPC3 channels interact directly with intracellular inositol 1,4,5-trisphosphate receptors...
Topics
- Androstadienes
- Animals
- Animals, Genetically Modified
- B-Lymphocytes
- Calcium
- Calcium Channels
- Cell Line
- Cells, Cultured
- Chickens
- DNA, Complementary
- Enzyme Inhibitors