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Article

Common polymorphisms and somatic mutations in human base excision repair genes in ovarian and endometrial cancers.

Mutation research - 1 Jan 2001

Pieretti M, Khattar N H, Smith S A

Abstract excerpt

The purpose of this study was to determine whether the human APEX and OGG1 genes, encoding proteins important in base excision repair (BER) of DNA, contain nucleotide sequence polymorphisms or are mutated somatically in tumors from women diagnosed with ovarian or endometrial cancer. Based upon the analysis of germline DNA from 83 individuals, 63 with ovarian cancer and 20 with endometrial cancer, we found two...

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Source

Identifiers

PMID: 11465542
DOI: 10.1016/s1383-5726(00)00002-9

Genes

OGG1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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