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Article

Apurinic/apyrimidinic endonuclease 1 polymorphisms are associated with ovarian cancer susceptibility in a Chinese population.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Oct 2013

Zhang Xiaohong, Xin Xiaoyan, Zhang Jianfang, Li Jia, Chen Biliang, Zou Wei

Abstract excerpt

OBJECTIVE: Apurinic/apyrimidinic endonuclease 1 (APE1) plays an essential role in the base excision repair pathway. Recent studies have shown that APE1 polymorphisms are associated with an increased risk for many types of cancers. This study investigated the association between APE1 polymorphisms and the susceptibility of ovarian cancer. METHODS: A case-control study was performed on 124 patients with ovarian...

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PMID: 24257553
DOI: 10.1097/IGC.0b013e3182a33f07

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