Article
Human Immunodeficiency Virus-1 Induces Loss of Contact Inhibition in Podocytes
1 Aug 2001
Abstract excerpt
Human immunodeficiency virus-associated nephropathy (HIVAN) affects up to 10% of HIV-positive black adults and children and is the leading cause of renal disease in infected individuals. The disease is characterized by proliferation of renal epithelial cells, both glomerular and tubular. Diseased kidneys are enlarged, and glomerular visceral epithelial cells (podocytes) express proliferation markers. In a...
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