Article
The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy.
Journal of the American Society of Nephrology : JASN - 1 Jan 1999
Barisoni L, Kriz W, Mundel P, D'Agati V
Abstract excerpt
Podocytes are highly differentiated, postmitotic cells, whose function is largely based on their complex cytoarchitecture. The differentiation of podocytes coincides with progressive expression of maturity markers, including WT-1, CALLA, C3b receptor, GLEPP-1, podocalyxin, and synaptopodin. In co...
Topics
- AIDS-Associated Nephropathy
- Adult
- Biomarkers
- Epithelial Cells
- Fetus
- Glomerulonephritis, Membranous
- Glomerulosclerosis, Focal Segmental
- Humans
- Ki-67 Antigen
- Kidney Glomerulus
- Microfilament Proteins
- Phenotype
- Proteinuria
- Receptors, Complement 3b
- Retrospective Studies
- Sialoglycoproteins