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Article

Functionally antagonistic sequences are required for normal autoregulation of Drosophila tra-2 pre-mRNA splicing.

Nucleic acids research - 15 Jul 2001

Chandler D S, McGuffin M E, Mattox W

Abstract excerpt

Expression of functional TRA-2 protein in the male germline of Drosophila is regulated through a negative feedback mechanism in which a specific TRA-2 isoform represses splicing of the M1 intron in the TRA-2 pre-mRNA. We have previously shown that the mechanism of M1 splicing repression is conserved between distantly related Drosophila species. Using transgenic fly strains, we have examined the effects on...

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Identifiers

PMID: 11452026
DOI: 10.1093/nar/29.14.3012
PMCID: PMC55796

Genes

TRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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