Article
Alternatively spliced transcripts of the sex-determining gene tra-2 of Drosophila encode functional proteins of different size.
The EMBO journal - 1 Nov 1990
Amrein H, Maniatis T, Nöthiger R
Abstract excerpt
The Drosophila transformer-2 gene (tra-2) is required for female sex determination in somatic cells and for spermatogenesis in male germ cells. We studied the organization of the tra-2 gene and characterized the transcripts in wild type and mutant animals. Two transcripts are detected in males an...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Genes
- Male
- Molecular Sequence Data
- Mutation
- Oligonucleotides
- Polymerase Chain Reaction
- Polymorphism, Genetic
- RNA Splicing
- RNA, Messenger
- Restriction Mapping
- Ribonucleoproteins
- Sex Determination Analysis