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Article

Generation of alternative Ultrabithorax isoforms and stepwise removal of a large intron by resplicing at exon-exon junctions.

Molecular cell - 1 Dec 1998

Hatton A R, Subramaniam V, Lopez A J

Abstract excerpt

Little is known about mechanisms that regulate and ensure accurate processing of complex transcription units with long introns. We investigate this in the Ultrabithorax gene of Drosophila. A consensus 5' splice site is regenerated at the junction between the first exon and a small internal exon (mI); this splice site is used in a developmentally regulated manner to remove mI during subsequent processing of the...

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PMID: 9885566
DOI: 10.1016/s1097-2765(00)80293-2

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