Article
Regulatory rearrangements and smg-sensitive alleles of the C. elegans sex-determining gene tra-1.
Developmental genetics - 1 Jan 1994
Zarkower D, De Bono M, Aronoff R, Hodgkin J
Abstract excerpt
The tra-1 gene is the terminal regulator in the sex determination pathway in C. elegans, directing all aspects of somatic sexual differentiation. Recessive loss-of-function (lf) mutations in tra-1 masculinize XX animals (normally somatically female), while dominant gain-of-function mutations femi...
Topics
- Alleles
- Animals
- Base Sequence
- Caenorhabditis elegans
- Chromosome Inversion
- DNA
- Female
- Gene Expression Regulation
- Gene Rearrangement
- Genes, Helminth
- Male
- Molecular Sequence Data
- RNA
- Sex Differentiation