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Article

The relationship between allelic imbalance on 17p, p53 mutation and p53 overexpression in head and neck cancer.

International journal of oncology - 1 Aug 2001

Götte K, Riedel F, Neubauer J, Schäfer C, Coy J F, Hörmann K

Abstract excerpt

The huge majority of head and neck squamous cell carcinoma (HNSCC) show alterations of p53 either on the genetic level or on the protein level. Allelic imbalance (AI)/loss of heterozygosity (LOH) on 17p at the p53 locus is frequent in HNSCC. However, the complex relationship between these phenomena is poorly understood in HNSCC. We investigated one group of 39 HNSCC for: a) allelic imbalance on 17p using 4...

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Share to Allelic Imbalance
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Expression Regulation, Neoplastic

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Share to Tumor Suppressor Protein p53

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Identifiers

PMID: 11445847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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