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Article

Sequence variation and linkage disequilibrium in the human T-cell receptor beta (TCRB) locus.

American journal of human genetics - 1 Aug 2001

Subrahmanyan L, Eberle M A, Clark A G, Kruglyak L, Nickerson D A

Abstract excerpt

The T-cell receptor (TCR) plays a central role in the immune system, and > 90% of human T cells present a receptor that consists of the alpha TCR subunit (TCRA) and the beta subunit (TCRB). Here we report an analysis of 63 variable genes (BV), spanning 553 kb of TCRB that yielded 279 single-nucleotide polymorphisms (SNPs). Samples were drawn from 10 individuals and represent four populations-African American,...

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Identifiers

PMID: 11438886
DOI: 10.1086/321297
PMCID: PMC1235310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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