Article
Sequence variation in the human T-cell receptor loci.
Immunological reviews - 1 Dec 2002
Mackelprang Rachel, Carlson Christopher S, Subrahmanyan Lakshman, Livingston Robert J, Eberle Michael A, Nickerson Deborah A
Abstract excerpt
Identifying common sequence variations known as single nucleotide polymorphisms (SNPs) in human populations is one of the current objectives of the human genome project. Nearly 3 million SNPs have been identified. Analysis of the relative allele frequency of these markers in human populations and the genetic associations between these markers, known as linkage disequilibrium, is now underway to generate a...
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