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Article

PCR-based genotyping and haplotype analysis of human TCRBV gene segment polymorphisms.

Immunogenetics - 1 Jan 1995

Charmley P, Concannon P

Abstract excerpt

There are at least 63 tandemly arranged human T-cell receptor (Tcr) beta-chain variable region (BV) gene segments, which have presumably arisen by repeated gene duplication events. The 5'-most half of the TCRBV gene loci is particularly complex in organization due to the presence of multiple interspersed members of the largest BV subfamilies, BV5, BV6, and BV13. Polymorphism and linkage relationships among these...

Topics

Alleles
Base Sequence
DNA Primers
DNA, Satellite
Genotype
Haplotypes
Humans
Linkage Disequilibrium
Molecular Sequence Data
Multigene Family
Point Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Receptors, Antigen, T-Cell, alpha-beta

Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 7672819
DOI: 10.1007/BF00176442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7672819-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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