Article
A mutation in the second largest subunit of TFIIIC increases a rate-limiting step in transcription by RNA polymerase III.
Molecular and cellular biology - 1 Jan 1994
Rameau G, Puglia K, Crowe A, Sethy I, Willis I
Abstract excerpt
In previous studies, we have shown that the PCF1-1 mutation of Saccharomyces cerevisiae suppresses the negative effect of a tRNA gene A block promoter mutation in vivo and increases the transcription of a variety of RNA polymerase III genes in vitro. Here, we report that PCF1 encodes the second l...
Topics
- Amino Acid Sequence
- Cloning, Molecular
- Fungal Proteins
- Genes, Fungal
- Kinetics
- Molecular Sequence Data
- Mutation
- Protein Conformation
- RNA Polymerase III
- Saccharomyces cerevisiae
- Transcription Factors
- Transcription Factors, TFIII
- Transcription, Genetic
- Transcription Factor TFIIIC