Article
Rbs1, a new protein implicated in RNA polymerase III biogenesis in yeast Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Apr 2015
Cieśla Małgorzata, Makała Ewa, Płonka Marta, Bazan Rafał, Gewartowski Kamil, Dziembowski Andrzej, Boguta Magdalena
Abstract excerpt
Little is known about the RNA polymerase III (Pol III) complex assembly and its transport to the nucleus. We demonstrate that a missense cold-sensitive mutation, rpc128-1007, in the sequence encoding the C-terminal part of the second largest Pol III subunit, C128, affects the assembly and stability of the enzyme. The cellular levels and nuclear concentration of selected Pol III subunits were decreased in...
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