Article
An x-ray diffraction investigation of corneal structure in lumican-deficient mice.
Investigative ophthalmology & visual science - 1 Jul 2001
Quantock A J, Meek K M, Chakravarti S
Abstract excerpt
PURPOSE: The corneas of mice homozygous for a null mutation in lumican, a keratan sulfate-containing proteoglycan, are not as clear as normal. In the present study, mutant corneas were examined by synchrotron x-ray diffraction to see what structural changes might lie behind the loss of transparency. METHODS: X-ray diffraction patterns were obtained from the corneas of 6-month-old and 2-month-old lumican-null and...
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