Article
Roles of lumican and keratocan on corneal transparency.
Glycoconjugate journal - 1 Jan 2000
Kao Winston W-Y, Liu Chia-Yang
Abstract excerpt
Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma. Both lumican and keratocan are essential for normal cornea morphogenesis during embryonic development and maintenance of corneal topography in adults. This is attributed to their bi-functional characteristic (protein moiety binding collagen fibrils to...
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