Article
Keratocan-deficient mice display alterations in corneal structure.
The Journal of biological chemistry - 13 Jun 2003
Liu Chia-Yang, Birk David E, Hassell John R, Kane Bradley, Kao Winston W-Y
Abstract excerpt
Keratocan (Kera) is a cornea-specific keratan sulfate proteoglycan (KSPG) in the adult vertebrate eye. It belongs to the small leucine-rich proteoglycan (SLRP) gene family and is one of the major components of extracellular KSPG in the vertebrate corneal stroma. The Kera gene is expressed in ocular surface tissues including cornea and eyelids during morphogenesis. Corneal KSPGs play a pivotal role in matrix...
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