Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of lumican in the corneal epithelium during wound healing.

The Journal of biological chemistry - 28 Jan 2000

Saika S, Shiraishi A, Liu C Y, Funderburgh J L, Kao C W, Converse R L, Kao W W

Abstract excerpt

Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and is also present in the connective tissues of other organs and embryonic corneal stroma as a glycoprotein. In normal unwounded cornea, lumican is expressed by stromal keratocytes. Our data show that injured mouse corneal epithelium ectopically and transiently expresses lumican during the early phase of wound healing,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelium, Corneal
Share to Antibodies
Share to Chondroitin Sulfate Proteoglycans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to In Situ Hybridization

Share to Mice, Inbred C57BL

Share to RNA, Messenger

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 10644720
DOI: 10.1074/jbc.275.4.2607
PMCID: PMC3580337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of lumican in the corneal epithelium during wound healing.PMID 10644720Read ↗

Impaired skin wound healing in lumican-null mice.Semantic proximity Read ↗

Response of Lens Epithelial Cells to Injury: Role of Lumican in Epithelial-Mesenchymal TransitionSemantic proximity Read ↗

Roles of lumican and keratocan on corneal transparency.Semantic proximity Read ↗

Altered collagen fibril formation in the sclera of lumican-deficient mice.Semantic proximity Read ↗

Targeted expression of a lumican transgene rescues corneal deficiencies in lumican-null mice.Semantic proximity Read ↗

Role of Cys41 in the N-terminal domain of lumican in ex vivo collagen fibrillogenesis by cultured corneal stromal cells.Semantic proximity Read ↗

Functions of lumican and fibromodulin: lessons from knockout mice.Semantic proximity Read ↗

Knockdown of Zebrafish Lumican Gene (zlum) Causes Scleral Thinning and Increased Size of Scleral CoatsSemantic proximity Read ↗

Ocular and Scleral Alterations in Gene-Targeted Lumican-Fibromodulin Double-Null MiceSemantic proximity Read ↗

Role of Decorin in the Lens and Ocular DiseasesSemantic proximity Read ↗

Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons.Semantic proximity Read ↗

Cell Therapy of Congenital Corneal Diseases with Umbilical Mesenchymal Stem Cells: Lumican Null MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.