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Article

Phenotypic alterations in Caki-1 cells as a consequence of TIMP-1 overexpression.

Cancer letters - 28 Aug 2001

Reid H M, McElligott A M, McGlynn H

Abstract excerpt

Maintenance of the extracellular matrix (ECM) is important for tissue integrity and cellular physiology. Normal ECM turnover is regulated by a balance between matrix metalloproteinases and their inhibitors, the tissue inhibitors of metalloproteinases (TIMPs). In metastasis, this balance favours increased ECM degradation. The objective of this study was to determine the effects of TIMP-1 overexpression on the...

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Identifiers

PMID: 11431108
DOI: 10.1016/s0304-3835(01)00520-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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