Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue inhibitor of metalloproteinases‐4 (TIMP‐4) regulates stemness in cervical cancer cells

30 Nov 2015

Abstract excerpt

Tissue inhibitor of metalloproteinase-4 (TIMP-4) belongs to a family of extracellular matrix (ECM) metalloproteinases inhibitors that are overexpressed in several cancers. However, the role of TIMP-4 during carcinogenesis is poorly understood. To evaluate TIMP-4 functions in carcinogenesis, stably transfected cells overexpressing this tissue inhibitor were used. Xenograft tumor growth, stem cell enrichment,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Protease and Inhibitor Mechanisms
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26618609
DOI: 10.1002/mc.22442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue inhibitor of metalloproteinases‐4 (TIMP‐4) regulates stemness in cervical cancer cellsPMID 26618609Read ↗

An integrative analysis reveals the prognostic and immunological role of TIMP gene family in pan-cancerSemantic proximity Read ↗

A Comprehensive Bioinformatics Analysis of TIMP2 in Multiple MalignanciesSemantic proximity Read ↗

Biological and Clinical Significance of TIMPs Expression in Breast Cancer: a Bioinformatic AnalysisSemantic proximity Read ↗

Tissue Inhibitor of Metalloproteinases-4. The road less traveledSemantic proximity Read ↗

The Role of Tissue Inhibitors of Metalloproteinases in Tumorigenesis and MetastasisSemantic proximity Read ↗

Cancer-Associated Fibroblasts induce aggressive stem cell phenotype and chemoresistance in cervical tumoroid-fibroblast co-culture system via upregulating CK17 expressionSemantic proximity Read ↗

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancerSemantic proximity Read ↗

Cancer Gene Therapy with Tissue Inhibitors of Metalloproteinases (TIMPs)Semantic proximity Read ↗

Whole Organism Profiling of the Timp Gene FamilySemantic proximity Read ↗

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state.Semantic proximity Read ↗

The TIMP protein family: diverse roles in pathophysiologySemantic proximity Read ↗

TGFA expression is associated with poor prognosis and promotes the development of cervical cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.