[Effects of TIMP-2 gene transfection on biological behaviors of a metastatic human lung carcinoma cell line].

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Article

[Effects of TIMP-2 gene transfection on biological behaviors of a metastatic human lung carcinoma cell line].

Zhonghua yi xue za zhi - 1 Sept 1997

Li H, Fang W, Shi Z

Abstract excerpt

OBJECTIVES: To explore the suppressive effects of tissue inhibitor of metalloproteinase 2 (TIMP-2) on malignant phenotype of human carcinoma cells and to evaluate its potential application in cancer gene therapy. METHODS: A man malian expression vector containing TIMP-2 cDNA was constructed and t...

Topics

Animals
Antineoplastic Agents
Carcinoma, Giant Cell
Collagenases
Gelatinases
Humans
Lung Neoplasms
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Metalloendopeptidases
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Metastasis
Phenotype
Tissue Inhibitor of Metalloproteinase-2
Transfection
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9772531

Genes

MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9772531-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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