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Article

Gender and age modify the association between APOE and AD-related neuropathology.

Neurology - 26 Jun 2001

Ghebremedhin E, Schultz C, Thal D R, Rüb U, Ohm T G, Braak E, Braak H

Abstract excerpt

OBJECTIVE: To assess the impact of apolipoprotein E (APOE) polymorphism on AD-related neurofibrillary tangle (NFT) formation and senile plaques (SP). METHODS: A sample of 729 routine autopsy brains (359 men, 370 women; age range, 60 to 99 years) was investigated. All brains were classified neuropathologically according to a procedure permitting differentiation of six NFT stages and three SP stages. APOE...

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Source

Identifiers

PMID: 11425936
DOI: 10.1212/wnl.56.12.1696

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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