Article
APOE and modulation of Alzheimer's and frontotemporal dementia.
Neuroscience letters - 19 Feb 2004
Boccardi M, Sabattoli F, Testa C, Beltramello A, Soininen H, Frisoni G B
Abstract excerpt
To investigate the difference in the morphologic expression of frontotemporal dementia (FTD) and Alzheimer's disease (AD) in patients carrying and not carrying the epsilon4 allele of APOE, MR images of 26 controls, 18 AD patients (11 carrying the epsilon4 allele, seven non-carriers), and eight FTD (two carriers, six non-carriers) were compared using voxel by voxel analysis. Greater atrophy was found in the...
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