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Article

Study of a novel hypervariable region in hepatitis C virus (HCV) E2 envelope glycoprotein.

Virology - 1 Sept 2006

Troesch Myriam, Meunier Isabelle, Lapierre Pascal, Lapointe Normand, Alvarez Fernando, Boucher Marc, Soudeyns Hugo

Abstract excerpt

A large share of hepatitis C virus amino acid sequence variation is concentrated within two hypervariable regions located at the N-terminus of the E2 envelope glycoprotein (HVR1 and HVR2). Interhost and intrahost comparison of 391 E2 sequences derived from 17 subjects infected with HCV using amino acid entropy revealed clustering of amino acid variability at a third site (residues 431-466), which was termed HVR3....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16781757
DOI: 10.1016/j.virol.2006.05.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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