Article
Full-length characterization of hepatitis C virus subtype 3a reveals novel hypervariable regions under positive selection during acute infection.
Journal of virology - 1 Nov 2009
Humphreys Isla, Fleming Vicki, Fabris Paolo, Parker Joe, Schulenberg Bodo, Brown Anthony, Demetriou Charis, Gaudieri Silvana, Pfafferott Katja, Lucas Michaela, Collier Jane, Huang Kuan-Hsiang Gary, Pybus Oliver G, Klenerman Paul, Barnes Eleanor
Abstract excerpt
Hepatitis C virus subtype 3a is a highly prevalent and globally distributed strain that is often associated with infection via injection drug use. This subtype exhibits particular phenotypic characteristics. In spite of this, detailed genetic analysis of this subtype has rarely been performed. We performed full-length viral sequence analysis in 18 patients with chronic HCV subtype 3a infection and assessed...
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