Article
DnaA boxes in the P1 plasmid origin: the effect of their position on the directionality of replication and plasmid copy number.
Journal of molecular biology - 29 Jun 2001
Park K, Chattoraj D K
Abstract excerpt
The DnaA protein is essential for initiation of DNA replication in a wide variety of bacterial and plasmid replicons. The replication origin in these replicons invariably contains specific binding sites for the protein, called DnaA boxes. Plasmid P1 contains a set of DnaA boxes at each end of its origin but can function with either one of the sets. Here we report that the location of origin-opening, initiation...
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